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Vitiligo + Antioxidants

Posted by DJ on March 19, 2011 at 7:01pm

Below is a link to an interesting research study.  

 

The article states "Research at the molecular level has demonstrated a deficiency of antioxidant substances in the vitiliginous skin."

 

Efficacy of antioxidants as an adjunct to photochemotherapy in vitiligo: A case study of 30 patients

 

Link To Research Article

http://www.ijdvl.com/article.asp?issn=0378-6323;year=2002;volume=68;issue=4;spage=202;epage=205;aulast=Jayanth

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Replies

  • DJ March 26, 2011 at 4:11am

    Great Research Paper.

     

    http://www.centro-lavalle.com/edu/wp-content/uploads/2010/05/Oxidat...

     

    "Therefore, probably the treatment of these individuals (vitiligo patients) with antioxidants can help prevent or cure the condition."

  • Bamsegutt March 20, 2011 at 9:35pm

     

    Thanks again for sharing this research…Many times it has been claimed that there is high level of hydrogin peroxide and less level of enzym catalese with us vitiligo peatents , this creates high free radicals on the skin which leads to melanocyte damage.

    What do we have to do to correct and balance this problem????????



    • DJ > Bamsegutt March 21, 2011 at 6:00am

      Many researchers believe that melanocyte damage is taking place due to oxidative stress (free radicals).  Maybe this is why ginkgo biloba (an herb with antioxidant properties) has an effect on arresting the spread of vitiligo.

       

      "Ginkgo leaves contain two types of chemicals (flavonoids and terpenoids) believed to have potent antioxidant properties. Antioxidants are substances that scavenge free radicals -- compounds in the body that damage cell membranes, tamper with DNA, and even cause cell death."

      http://www.umm.edu/altmed/articles/ginkgo-biloba-000247.htm

       

      This leads to the possibility that the consumption of antioxidants such as pomegranate may lower free radicals found within vitiliginous skin.

       

      what do you think?

      • DJ > DJ March 21, 2011 at 6:18am

        so confused.. the above researchers believe there is no link between melanocyte damage and oxidative stress, while the below researchers believe there is a clear link between the two.

         

        "Our results show that blood levels of Vit E, SOD, GSH, GSH-Px activity, LIP and PL-FA in AVP were not significantly different from those of healthy age matched controls, indicating that melanocyte damage in vitiligo is not linked with a generalized oxidative stress."

         

        http://www.ncbi.nlm.nih.gov/pubmed/8066016

         

        on the other hand.. these researchers write "This study demonstrated that antioxidant processes depletion (low TAS and low GPX activity) is clearly involved with vitiligo"

         

        http://www.e-ijd.org/article.asp?issn=0019-5154;year=2009;volume=54...

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