I have found information on the web where people claim to have reversed the depigmentation of Vitiligo if they take a well known cream only if they do so on the initial onset of a white spot appearing.
This seems to be more prevalent if the person being treated is young.
Can anyone add anything to this claim?
Replies
Hi Steve,
How are you?
I don't think it has to do with a person's age, but with the time the disease has been triggered. So that it's easier to treat a person who has recently been diagnosed with vitiligo.
Why?
Because the vitiligo causative factors have not caused an extensive internal damage yet.
Which damage?
Basically the oxidative stress, whose vitiligo is a side effect.
Vitiligo is usually caused on pre-disposed people (1) by the action of friction and trauma in certain regions like knees, elbows, hands, feet, wrists, around the eyes, forehead and around the mouth, (2) facilitated by oxidative stress, and (3) accelerated by stress hormones.
Oxidative stress is a complex concept. It's essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. The major factors for consideration are: food allergy, poor diet, leaky gut and dysbiosis (parasites, candida, h-pylori, yeast, fungus, etc.).
→ Additionally, onset can be caused by toxic chemical compounds and pollutants within your body, hydrogenated fats, all kinds of pollution (air, water and food), oils that have been heated to very high temperatures, cigarette smoke (directly inhaled or secondhand), dehydration, too much sugar, too much animal protein in your diet, geophysical stress (like living near power lines or waste dumps), viral infections, preservatives in your food, drugs (over the counter and prescription), artificial food colorings and flavorings, plastics and phthalates, chemical cleaning supplies, chlorinated water (that you drink, shower or swimming), alcohol, pesticides in your food, radiation exposure, psychological and emotional stress, endurance exercise and, rather incredibly, physical traumas within the body (muscle damaging anaerobic training, trauma or injury to muscle, bone and skin).
→Oxidative stress causes defects in the membrane integrity, also causes lipid peroxidation, generates hydrogen peroxide in the skin that mutates mitochondrial DNA. All this weakens cell adhesion. NSV starts because people who are predisposed to have dysfunctional melanocytes, start having mutated melanocytes. Their cell adhesion becomes compromised.
More details at: http://www.vitiligomap.com/
So, it's possible to revert patches in the initial onset of vitiligo by being vigilant in addressing and avoiding the main causes as detailed below:
1-Physical traumas ⇒ friction, injuries, itches, scratches, allergies, sun burns, impacts, violent moves, hits, punches, kicks, etc.
2-Oxidative stress ⇒ food allergy, poor diet, leaky gut and dysbiosis (parasites, candida, h-pylori, yeast, fungus, etc.). Effects are lipid peroxidation, hydrogen peroxide, ROS, and mitochondrial DNA mutation.
3-Stress hormones ⇒ generated by psychological and emotional systematic stress.
Many thanks for this information!
I wish I had joined this forum sooner. I think that the food allergy 'Trauma' and poor diet do play an important factor with this condition.
Strange thing here that my brother also has the condition. He suffered third degree burns to his one foot as a child, and only when he was in his late 30's did he get Vitiligo. He was left with a white patch or scar at the time of the incident which remained dormant for all those years. He is basically 80% de-pigmented now.
Obviously our family is has an immune system that is not capable of handling trauma events to the skin.
Causes 1, 2 and 3 have to work together on predisposed people in order to trigger vitiligo. So, maybe your brother took a while to be in an oxidative stress condition. When it happened, added to his trauma and any eventual emotional/psychological stress, the disease was finally triggered.
See the suggested model below: